Anti-CCL4 Rabbit Polyclonal Antibody for WB, ELISA - P14097

Core Product Specifications and Parameters

Biological Background: CCL4 Function and Localization

• CCL4, also known as MIP-1-beta, ACT-2, and Scya4, is a C-C motif chemokine encoded by the Ccl4 gene in mice.
• It functions as a monokine with inflammatory and chemokinetic properties, playing a role in immune cell recruitment and activation.
• CCL4 is a secreted protein, released into the extracellular space to mediate chemotaxis.
• Contains conserved disulfide bonds characteristic of the chemokine family, contributing to its structural stability.
• Belongs to the intercrine beta (chemokine CC) family, as highlighted by keywords Chemotaxis, Cytokine, and Inflammatory response.

Experimental Guidance and Technical Tips

• For Western blotting, note that mouse CCL4 has a predicted molecular weight of ~10 kDa; select gel and transfer conditions suitable for low-molecular-weight proteins.
• The immunogen corresponds to amino acids 24–92, which may represent the mature secreted form; consider this when interpreting band patterns.
• For ELISA applications, validate antibody performance in the relevant biological matrix (e.g., serum, cell culture supernatant) to ensure specificity.
• As a polyclonal antibody, lot-to-lot consistency should be verified; include appropriate positive and negative controls in all assays.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio streamlines procurement of high-quality IVD raw materials, offering validated antibodies, bulk ancillary reagents, and rare-target sourcing for diagnostic manufacturers and research laboratories worldwide. This anti-CCL4 antibody supports studies of chemokine-mediated inflammation and chemotaxis, and we can supply matched antibody pairs, recombinant proteins, and optimized reagents to accelerate your assay development. Whether you need off-the-shelf polyclonals or custom monoclonal solutions, our sourcing network bridges your project from concept to clinic.