Anti-CAMK1G Polyclonal Antibody for WB, ELISA - Q96NX5

Core Product Specifications and Parameters

Biological Background: CAMK1G Function and Localization

• CAMK1G (Calcium/calmodulin-dependent protein kinase type 1G) is a serine/threonine-protein kinase belonging to the CaM kinase family.
• Also known as CaM kinase I gamma, CaM-KI gamma, CaMKI gamma, CaMKIG, and CLICK III (CaMK-like CREB kinase III).
• Functions in a calcium-triggered signaling cascade; in vitro, it phosphorylates transcription factor CREB1 (By similarity).
• Localizes to the cytoplasm, Golgi apparatus membrane, and cell membrane.
• Predominantly expressed in brain, with high expression in forebrain neocortex, striatum, and limbic system; also detected at lower levels in skeletal muscle, kidney, spleen, and liver.
• Contains conserved ATP-binding, calmodulin-binding, and kinase domains; undergoes prenylation for membrane anchoring.
• Alternative splicing generates multiple isoforms.
• Keywords: ATP-binding, calmodulin-binding, kinase, serine/threonine-protein kinase, prenylation, lipoprotein, membrane, Golgi apparatus, cytoplasm, reference proteome.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the C-terminal region (aa 217–476), which may detect multiple isoforms; consider validating in your specific sample system.
• For western blot (WB), use appropriate positive controls (e.g., brain tissue lysates) due to enriched expression in the central nervous system.
• ELISA: consider employing purified recombinant CAMK1G protein as a standard; cross-reactivity with mouse and rat suggests utility in rodent model studies.
• Verify antibody reactivity in your species of interest, as cross-reactivity is reported but may vary with sample type or experimental conditions.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers and research laboratories with a comprehensive portfolio of IVD raw materials. For CAMK1G-related projects, we offer validated polyclonal and monoclonal antibodies, recombinant proteins, and ancillary reagents tailored to neuroscience and kinase signaling research. Our one-stop procurement model streamlines access to quality-controlled raw materials, from early-stage development to clinical application, helping you accelerate assay development and biomarker discovery.