Anti-BRCC2/BLID Rabbit Polyclonal Antibody for WB, IF/ICC, ELISA - Q8IZY5

Core Product Specifications and Parameters

Biological Background: BRCC2/BLID Function and Localization

• BRCC2/BLID, also known as BH3-like motif-containing cell death inducer or Breast cancer cell protein 2, is a proapoptotic molecule.
• It functions through the caspase-dependent mitochondrial pathway of cell death.
• The protein contains a BH3-like motif, characteristic of Bcl-2 family proteins involved in apoptosis.
• BRCC2/BLID localizes to both the cytoplasm and mitochondria.
• It is ubiquitously expressed across human tissues.
• Key biological processes associated with BRCC2/BLID include apoptosis.

Experimental Guidance and Technical Tips

• The immunogen for this antibody is a recombinant fusion protein spanning amino acids 1-108 of human BRCC2/BLID (NP_001001786.2), which may enable detection of the full-length endogenous protein.
• In Western blot analysis, a band of approximately 12 kDa is expected in lysates from human, mouse, and rat origin.
• For immunofluorescence and ELISA applications, we recommend optimizing the antibody dilution and experimental conditions in your specific system.
• Consider including appropriate controls to validate specificity and performance in your assays.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your one-stop partner for IVD raw-material sourcing, offering a comprehensive portfolio of validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary reagents. For apoptosis and cell death research, we can assist in procuring rare-target raw materials and provide technical consulting to streamline assay development. Contact us to discuss your specific sourcing and project needs.