Anti-BPIFB2 Rabbit Polyclonal Antibody for WB, ELISA - Q8N4F0

Core Product Specifications and Parameters

Biological Background: BPIFB2 Function and Localization

• BPIFB2 is a member of the BPI fold-containing family B, sharing structural similarity with bactericidal/permeability-increasing proteins, which are implicated in lipid binding and innate immunity.
• Alternative names include RYSR, BPIL1 (BPI-like 1), and LPLUNC2 (long palate, lung and nasal epithelium carcinoma-associated protein 2).
• The protein is predicted to be secreted, consistent with the presence of a signal peptide and its annotation as an extracellular protein.
• Tissue expression is predominantly in tonsils, with heightened levels in hypertrophic tonsils; fetal liver shows only trace amounts.
• Post-translational modifications include glycosylation and phosphorylation, and the protein contains disulfide bonds, as indicated by UniProt keywords.
• The calculated molecular weight is approximately 49 kDa, matching the product specification.
• The BPIFB2 gene (also known as C20orf184) resides on human chromosome 20.

Experimental Guidance and Technical Tips

• The immunogen is a recombinant fusion protein spanning amino acids 40–340 of human BPIFB2; this region may contain conserved epitopes that explain cross-reactivity with mouse and rat.
• Recommended applications are Western blot (WB) and ELISA. Optimal antibody dilutions should be determined empirically by the end user.
• As a secreted protein, consider using appropriate lysis buffers that retain soluble proteins, or analyze cell culture supernatants if studying secretion.
• Validate specificity with relevant controls, such as knockdown or knockout lysates, or tissues with known expression (e.g., human tonsil).
• Antibody is shipped on ice to maintain stability; store in aliquots at the recommended temperature to avoid degradation from repeated freeze-thaw cycles.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your one-stop sourcing partner for IVD raw materials, connecting diagnostic manufacturers and research teams with high-quality antibodies, proteins, and ancillary reagents. This BPIFB2 polyclonal antibody exemplifies our portfolio for innate immunity and mucosal biology studies. From validated antibody pairs and bulk monoclonals to rare-target raw material procurement and technical consulting, we support every stage from concept to clinic.