Anti-BCL2L14/BCLG Rabbit Polyclonal Antibody for WB, IF, ELISA - Q9BZR8

Core Product Specifications and Parameters

Biological Background: BCL2L14/BCLG Function and Localization

• BCL2L14 encodes the apoptosis facilitator Bcl-2-like protein 14, also known as apoptosis regulator Bcl-G.
• As a Bcl-2-like protein, it is predicted to function in the regulation of apoptosis.
• Isoform 1 is widely expressed, while isoform 2 is testis-specific, indicating tissue-specific roles.
• Functionally, BCL2L14 plays a role in apoptosis, likely promoting cell death.
• The protein localizes to the cytoplasm, including the cytosol and endomembrane system.
• BCL2L14 is subject to phosphorylation, suggesting regulation by signaling pathways.
• Alternative splicing generates multiple isoforms, which may have distinct functions.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the full-length BCL2L14 protein (aa 1–327); consider this when designing epitope-specific assays.
• For western blotting, expect a band around 37 kDa; minor shifts may occur due to phosphorylation or isoform differences.
• The antibody has been validated for immunofluorescence/immunocytochemistry; optimize fixation and permeabilization conditions for your specific cell type.
• It is suitable for ELISA; verify coating and detection conditions using relevant positive controls.
• Demonstrated cross-reactivity with mouse and rat samples; however, alignment of the immunogen sequence against the target species is recommended to confirm epitope conservation.
• As a rabbit polyclonal antibody, it provides multi-epitope recognition, enhancing sensitivity but requiring careful validation for each application.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with streamlined access to validated IVD raw materials, including apoptosis pathway antibodies like this BCL2L14/BCLG polyclonal antibody. Our technical and supply teams support procurement of antibody pairs, monoclonal/polyclonal reagents, and ancillary biochemicals, and can assist in sourcing rare-target raw materials to advance your projects from concept to clinic.