Anti-BCL2L14/BCLG Rabbit Monoclonal Antibody for WB, IHC-P, ELISA - Q9BZR8

Core Product Specifications and Parameters

Biological Background: BCL2L14/BCLG Function and Localization

• BCL2L14, also known as Bcl-G, is an apoptosis facilitator belonging to the Bcl-2 protein family.
• The protein exists in at least two isoforms generated by alternative splicing: a widely expressed isoform 1 and a testis-specific isoform 2.
• BCL2L14 localizes primarily to the cytoplasm, including the cytosol and endomembrane system.
• It is classified as a phosphoprotein, suggesting regulation by phosphorylation.
• The Bcl-2 family members are key regulators of programmed cell death, and BCL2L14’s apoptotic function likely involves interactions at intracellular membranes.
• The protein has been identified through proteomics approaches, confirming its endogenous expression.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 1-250 of human BCL2L14, so the antibody is expected to recognize the N-terminal region of the protein. Consider this when designing epitope-specific assays.
• Validated for Western blot (WB), immunohistochemistry on paraffin sections (IHC-P), and ELISA. For IHC-P, antigen retrieval conditions may need optimization; test on relevant apoptosis-associated tissue samples.
• Cross-reacts with mouse and rat, making it suitable for preclinical studies in rodent models. Validate in the appropriate species-specific sample system.
• Since BCL2L14 plays a role in apoptosis, consider using the antibody in functional studies alongside apoptosis markers. Confirm expression and localization patterns in your experimental cell lines.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supplies this BCL2L14/BCLG rabbit monoclonal antibody as part of a broader portfolio for apoptosis research and IVD raw material sourcing. Beyond this antibody, CamelBio offers validated antibody pairs, bulk ancillary reagents, and assistance in sourcing rare target raw materials, supporting diagnostic manufacturers and labs from concept to clinic. Let CamelBio be your single procurement partner for reliable, high-quality immunoreagents.