Anti-BAG2 Polyclonal Antibody for WB & ELISA - O95816

Core Product Specifications and Parameters

Biological Background: BAG2 Function and Localization

• BAG2 (Bcl-2-associated athanogene 2) is a member of the BAG co-chaperone family that interacts with HSP70 and HSC70 chaperone proteins. Related references: PMID:9873016
• It functions as a nucleotide-exchange factor (NEF), promoting the release of ADP from HSP70/HSC70, thereby triggering client/substrate protein release. Related references: PMID:24318877 PMID:9873016
• The protein contains a coiled-coil domain and is subject to post-translational modifications including acetylation and phosphorylation.
• Alternative splicing generates multiple transcript variants of BAG2.
• BAG2 is involved in protein quality control and the regulation of chaperone-mediated protein folding and degradation.

Experimental Guidance and Technical Tips

• For Western blot, a band around 24 kDa is expected for human BAG2; consider standard polyclonal antibody dilutions and optimize for your sample system.
• The recombinant immunogen (aa 1–211) suggests the antibody may recognize both endogenous and overexpressed BAG2; validate cross-reactivity in your experimental model.
• For ELISA, direct or indirect detection protocols can be tested; confirm binding conditions with the relevant antigen.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one-stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. This Anti-BAG2 Polyclonal Antibody supports research into chaperone-mediated proteostasis, protein quality control, and related disease mechanisms. Beyond this product, CamelBio offers validated antibody pairs, bulk ancillary reagents, and custom sourcing for rare targets to accelerate your assay development.