Anti-AVPI1 Polyclonal Antibody for WB and ELISA - Q5T686

Core Product Specifications and Parameters

Biological Background: AVPI1 Function and Localization

• AVPI1 (Arginine vasopressin-induced protein 1), also designated VIP32, VIT32, or PP5395, is a 147-amino acid protein encoded by the AVPI1 gene (Gene ID: 60370).
• The protein may participate in the MAP kinase signaling pathway, potentially influencing cellular responses to external stimuli.
• AVPI1 has been implicated in the down-regulation of the epithelial sodium channel (ENaC), suggesting a role in ion homeostasis and fluid balance.
• Functional links to cell cycling indicate that AVPI1 might be involved in the regulation of cell proliferation and division.
• Proteomics-based identification and inclusion in the reference proteome highlight its conserved expression and potential significance across biological contexts.

Experimental Guidance and Technical Tips

• The immunogen covers amino acids 1–147, corresponding to the full-length human AVPI1 protein; the antibody is expected to recognize the native target in relevant sample systems.
• For Western blotting (WB), consider using whole-cell lysates from human, mouse, or rat tissues; validate detection of a band near 17 kDa and include appropriate loading controls.
• In ELISA applications, optimize coating antigen and antibody dilutions to achieve optimal signal-to-noise ratios.
• Verify specificity by knockdown or knockout controls if possible, particularly when examining potential isoforms or cross-reactive bands.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers and research laboratories with a comprehensive portfolio of IVD raw materials, including validated antibody pairs, optimized polyclonal antibodies, and bulk ancillary reagents. Through agile sourcing capabilities, we facilitate convenient access to rare-target raw materials such as this anti-AVPI1 antibody, addressing needs in cell signaling and ion channel investigations. Let CamelBio be your procurement partner in streamlining assay development from concept to clinic.