Anti-ATRNL1 Polyclonal Antibody for WB and ELISA - Q5VV63

Core Product Specifications and Parameters

Biological Background: ATRNL1 Function and Localization

• ATRNL1 (Attractin-like protein 1) is a transmembrane protein encoded by the ATRNL1 gene, also known as ALP, bA338L11.1, or bA454H24.1.
• It contains structural domains including EGF-like domains, Kelch repeats, laminin EGF-like domains, and a C-type lectin domain, suggesting roles in protein-protein interactions and signaling.
• The protein features a signal peptide and a transmembrane helix, consistent with its membrane localization.
• ATRNL1 may play a role in melanocortin signaling pathways that regulate energy homeostasis.
• Alternative splicing generates multiple isoforms (UniProt keyword).
• It is post-translationally modified by glycosylation and contains disulfide bonds.

Experimental Guidance and Technical Tips

• The immunogen (recombinant fragment spanning amino acids 53–160) covers an N-terminal region that is likely conserved between human and mouse, supporting observed cross-reactivity.
• For Western blot (WB), consider optimizing sample preparation and antibody dilution; the predicted molecular weight is approximately 153 kDa, but alternative isoforms or glycosylation may cause shift.
• For ELISA, the polyclonal nature provides multiple binding sites; validate specificity with appropriate controls.
• Always validate the antibody in the relevant experimental model to confirm performance.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with a comprehensive one-stop sourcing platform for IVD raw materials. This anti-ATRNL1 polyclonal antibody supports energy homeostasis and melanocortin signaling research. CamelBio offers bulk supplies of validated antibodies, optimized monoclonal/polyclonal antibody pairs, and rare target raw-material procurement to accelerate your assay development from concept to clinic.