Anti-ASNS Rabbit Monoclonal Antibody for WB, ELISA - P08243

Core Product Specifications and Parameters

Biological Background: ASNS Function and Localization

• ASNS encodes Asparagine synthetase [glutamine-hydrolyzing], also known as Cell cycle control protein TS11 (P08243).
• The enzyme functions as a glutamine-dependent ligase, catalyzing ATP-dependent synthesis of asparagine from aspartate and glutamine, a key step in asparagine biosynthesis.
• It is implicated in both amino acid metabolism and cell cycle regulation, reflecting its dual roles.
• Alternative splicing generates multiple isoforms, potentially contributing to functional diversity.
• Post-translational modifications include acetylation and phosphorylation, which may regulate activity or stability.
• Disease-associated variants of ASNS are linked to intellectual disability, highlighting its clinical relevance.
• The protein is part of the reference proteome and has been identified in large-scale proteomics analyses.

Experimental Guidance and Technical Tips

• The immunogen peptide (aa 450-550) lies in a region likely conserved across species; confirmed cross-reactivity with mouse and rat supports broad utility.
• This monoclonal antibody is recommended for WB and ELISA; for other applications, pilot experiments and optimization are advised.
• Include appropriate positive and negative controls (e.g., knockdown cell lysates) to verify target specificity in WB.
• The predicted molecular weight is approximately 64 kDa; confirm band migration with pre-stained markers.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio streamlines IVD raw material procurement with validated antibody pairs, optimized monoclonal/polyclonal antibodies, and ancillary reagents. This ASNS rabbit monoclonal antibody serves research in amino acid metabolism, cell cycle biology, and genetic disease. For rare target sourcing or comprehensive supply support, CamelBio bridges concept-to-clinic workflows with reliable B2B solutions.