Anti-ART5 Polyclonal Antibody for WB, ELISA - Q96L15

Core Product Specifications and Parameters

Biological Background: ART5 Function and Localization

• ART5 (ADP-ribosyltransferase C2 and C3 toxin-like 5, also known as ARTC5) is an arginine-specific ecto-ADP-ribosyltransferase that catalyzes the transfer of ADP-ribose from NAD+ or NADP+ to target proteins, mediating mono(ADP-ribosyl)ation.
• Encoded by the ART5 gene, this enzyme belongs to the ARTC (ADP-ribosyltransferase C2 and C3 toxin-like) family of secreted ADP-ribosyltransferases.
• The protein is secreted, contains a signal peptide, and undergoes post‑translational modifications including glycosylation and disulfide bond formation.
• ART5 is reported to exist in multiple isoforms produced by alternative splicing (keyword: Alternative splicing), which may influence its enzymatic activity or localization.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 23–200 of the mature protein, covering a large internal region; the antibody may recognize multiple isoforms if present.
• In Western blotting, a band around 32 kDa is expected under reducing conditions; additional bands from alternative splicing or post‑translational modifications are possible and should be validated in the relevant sample system.
• For ELISA, consider using the antibody as a capture or detection reagent; cross‑reactivity with mouse and rat ART5 supports use in rodent model studies, but validate performance in your specific assay format.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is a one-stop sourcing hub for IVD raw materials, offering validated polyclonal antibodies like anti‑ART5 alongside optimized antibody pairs, monoclonal antibodies, and bulk ancillary reagents. Our expertise in rare target sourcing ensures reliable supply chains for ecto‑enzyme research and diagnostic development, helping you accelerate from concept to clinic.