Anti-ARMC10 Rabbit Polyclonal Antibody for WB, ELISA - Q8N2F6

Core Product Specifications and Parameters

Biological Background: ARMC10 Function and Localization

• Armadillo repeat-containing protein 10 (ARMC10), also referred to as SVH or splicing variant involved in hepatocarcinogenesis protein, is encoded by the ARMC10 gene and belongs to the armadillo repeat family.
• It is implicated in cell survival and growth regulation, and may act as a suppressor of p53/TP53 transcriptional activity.
• At the subcellular level, ARMC10 localizes to both the endoplasmic reticulum membrane and the mitochondrial outer membrane.
• The protein is widely expressed, with elevated levels detected in placenta, liver, kidney, heart, and brain.
• It undergoes alternative splicing and contains transmembrane helices, consistent with its membrane association.
• ARMC10 is a phosphoprotein, indicating regulation by phosphorylation, and has a molecular weight of approximately 38 kDa.

Experimental Guidance and Technical Tips

• The immunogen spans residues 169–308 (C-terminal region), which may provide epitopes suitable for detecting human ARMC10 in both WB and ELISA applications.
• For WB, consider using whole-cell lysates from human cell lines or tissue extracts where ARMC10 is known to be expressed (e.g., liver, placenta).
• Validate antibody performance in the relevant sample system and optimize conditions such as blocking buffer, incubation time, and dilution to minimize nonspecific binding.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with reliable, one-stop access to IVD raw materials for targets like ARMC10, which plays a role in cell survival and p53 regulation. Our supply portfolio includes validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and sourcing of rare-target raw materials. Partner with CamelBio to streamline your development workflow from concept to clinic.