Anti-AIP Rabbit Polyclonal Antibody for WB and ELISA - O00170

Core Product Specifications and Parameters

Biological Background: AIP Function and Localization

• AIP (AH receptor-interacting protein) is also known as ARA9, XAP2, XAP-2, FKBP16, FKBP37, and SMTPHN; it is encoded by the AIP (XAP2) gene in humans.
• It may play a positive role in aryl hydrocarbon receptor (AHR)-mediated signaling, possibly by influencing ligand receptivity and/or nuclear targeting of AHR.
• AIP acts as a cellular negative regulator of the hepatitis B virus (HBV) X protein.
• The protein contains TPR repeat domains, which are often involved in protein-protein interactions.
• Subcellular localization is predominantly cytoplasmic.
• AIP is widely expressed, with higher levels observed in heart, placenta, and skeletal muscle; it is not expressed in the liver.
• Post-translational modifications include phosphorylation, and the protein is linked to Cushing syndrome in certain contexts.

Experimental Guidance and Technical Tips

• The immunogen used to generate this antibody comprises the full-length human AIP protein (amino acids 1–330), which may provide broad epitope coverage.
• For Western blot (WB), consider optimizing lysate preparation from tissues with high AIP expression, such as heart, placenta, or skeletal muscle.
• In ELISA, the antibody may be suitable for detecting recombinant or native AIP; validate with appropriate positive and negative controls in your sample system.
• When working with human, mouse, or rat samples, verify cross-reactivity under your specific experimental conditions, as performance can vary.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers and research laboratories by offering a comprehensive portfolio of IVD raw materials, including validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary reagents. As a one-stop sourcing partner, we help streamline procurement for targets like AIP, which is relevant to AHR signaling and HBV research. Whether you need rare-target raw materials or technical consultation from concept to clinic, CamelBio is committed to bridging your supply needs efficiently.