Anti-ACTR10 Rabbit Polyclonal Antibody for WB and ELISA - Q9NZ32

Core Product Specifications and Parameters

Biological Background: ACTR10 Function and Localization

• ACTR10, also designated Arp11 or hARP11, is an actin-related protein and a subunit of the dynactin complex.
• The dynactin complex is a critical activator of the molecular motor dynein, facilitating ultra-processive microtubule-based transport.
• ACTR10 functions in cytoplasmic cargo trafficking by linking dynein to various organelles and vesicles.
• Subcellularly, ACTR10 localizes to the cytoplasm and associates with the cytoskeleton.
• The protein has a predicted molecular weight of approximately 46.3 kDa, consistent with the observed 46 kDa band in western blots.
• Structural studies (3D-structure keyword) have contributed to understanding its role in dynactin assembly.

Experimental Guidance and Technical Tips

• Given that the immunogen corresponds to residues 218-417 of human ACTR10, the antibody likely recognizes an epitope in the C-terminal half of the protein. Consider testing in lysates from human, mouse, or rat cells, as cross-reactivity is reported.
• For western blotting, a band around 46 kDa is expected. Validate specificity by using ACTR10 knockdown or knockout controls if available.
• In ELISA applications, use the recombinant immunogen or purified protein as a positive control to assess binding.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is a dedicated IVD raw-material sourcing partner, offering a comprehensive range of antibodies, antigens, and ancillary reagents for assay development and manufacturing. This anti-ACTR10 antibody is suitable for research into dynein-mediated transport and dynactin complex biology, and CamelBio can support your project with validated antibody pairs, optimized clones, and bulk-order logistics.