Anti-ACAT2 Rabbit Polyclonal Antibody for WB, IHC-P, IF/ICC, ELISA - Q9BWD1

Core Product Specifications and Parameters

Biological Background: ACAT2 Function and Localization

• ACAT2 (Acetyl-CoA acetyltransferase, cytosolic), also known as cytosolic acetoacetyl-CoA thiolase, is encoded by the ACAT2 gene (GeneID: 39) in humans.
• ACAT2 is a cytosolic thiolase enzyme involved in the biosynthetic pathway of cholesterol.
• ACAT2 localizes to the cytoplasm and cytosol, consistent with its role in cholesterol biosynthesis.
• ACAT2 belongs to the thiolase family of acyltransferases and undergoes alternative splicing.
• The protein undergoes acetylation, a modification that may regulate its activity.
• The ACAT2 protein has been structurally characterized (3D-structure), and its sequence has been verified by direct protein sequencing and proteomics identification.

Experimental Guidance and Technical Tips

• Based on the immunogen design (synthetic peptide spanning residues 159–277 of human ACAT2), this polyclonal antibody may recognize native and denatured ACAT2 protein in Western blot, immunohistochemistry (paraffin sections), immunofluorescence/immunocytochemistry, and ELISA.
• Cross-reactivity with mouse and rat ACAT2 is indicated; however, it is recommended to validate performance in the specific experimental context.
• The expected molecular weight of human ACAT2 is approximately 41 kDa; use appropriate loading controls and confirm band specificity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides one-stop access to IVD raw materials, including this anti-ACAT2 antibody, for research and diagnostic development in cholesterol metabolism and related disorders. With validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target sourcing, CamelBio supports your projects from concept to clinic. Explore our portfolio to streamline your procurement of high-quality immunological reagents.