Anti-ABTB1 Rabbit Polyclonal Antibody for WB, ELISA - Q969K4

Core Product Specifications and Parameters

Biological Background: ABTB1 Function and Localization

• ABTB1 (Ankyrin repeat and BTB/POZ domain-containing protein 1), also known as elongation factor 1A-binding protein (EF1ABP), BPOZ, BTB3, BTBD21, or PP2259.
• Acts as a mediator of the PTEN growth-suppressive signaling pathway and may play a role in developmental processes.
• Contains an N-terminal BTB/POZ domain, C-terminal ankyrin repeats, and a coiled-coil region, which facilitate protein-protein interactions.
• Localizes primarily to the cytoplasm.
• Ubiquitously expressed in fetal tissues, including heart, brain, liver, and kidney; lower expression persists in adult heart.
• Binds elongation factor 1A, suggesting involvement in regulating protein biosynthesis.

Experimental Guidance and Technical Tips

• The immunogen covers the N-terminal 140 amino acids; consider validating detection specificity in the relevant sample system.
• For Western blotting, optimize lysate preparation and antibody dilution using positive control lysates from human, mouse, or rat tissues expressing ABTB1.
• This antibody may be suitable for ELISA applications; pair with an appropriate detection antibody and validate under your assay conditions.
• Cross-reactivity with mouse and rat is indicated; performance in these species should be empirically confirmed.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers a seamless sourcing experience for IVD raw materials, from early research to commercial production. For ABTB1-related studies in tumor suppression and developmental biology, we supply validated antibody pairs, optimized polyclonal antibodies, bulk ancillary reagents, and rare target raw-material sourcing. Partner with us to accelerate your assay development pipeline.