ABCF3 Rabbit Polyclonal Antibody for WB, IHC-P, ELISA - Q9NUQ8

Core Product Specifications and Parameters

Biological Background: ABCF3 Function and Localization

• ABCF3 (ATP-binding cassette sub-family F member 3) is a member of the ABC transporter family, characterized by ATP-binding cassette domains.
• The protein exhibits antiviral activity against flaviviruses such as West Nile virus (WNV) when co-expressed with OAS1B.
• ABCF3 contains nucleotide-binding domains and is annotated with keywords: ATP-binding, Nucleotide-binding, Repeat.
• Post-translational modifications include acetylation and phosphorylation (based on keywords: Acetylation, Phosphoprotein).
• Alternative splicing produces multiple isoforms (keyword: Alternative splicing).
• The protein has been identified in proteomics studies (keyword: Proteomics identification).
• No specific subcellular localization or tissue specificity information is currently available.

Experimental Guidance and Technical Tips

• The immunogen used is a recombinant fusion protein covering amino acids 1-200 of human ABCF3, suggesting targeting the N-terminal region. Consider this region for antibody specificity.
• For Western blot (WB) applications, the predicted molecular weight is ~80 kDa. Validate band size in relevant sample systems.
• The antibody has been tested in WB, IHC-P, and ELISA. For IHC-P, consider antigen retrieval optimization and validation in appropriate tissue controls.
• Cross-reactivity has been confirmed with human, mouse, and rat. For other species, sequence homology should be assessed before use.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers one-stop access to IVD raw materials, from validated antibody pairs to optimized polyclonal and monoclonal antibodies. ABCF3 is involved in antiviral defense and is a target for research in flavivirus infection. For your diagnostic and research needs, CamelBio can source bulk ancillary reagents and rare target raw materials, streamlining your development from concept to clinic.